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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
7 DPC

10 matching records from 10 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mesp1  mesoderm posterior 1   (Synonyms: bHLHc5)
Results  Reference
1J:311976 Ajima R, Sakakibara Y, Sakurai-Yamatani N, Muraoka M, Saga Y, Formal proof of the requirement of MESP1 and MESP2 in mesoderm specification and their transcriptional control via specific enhancers in mice. Development. 2021 Oct 15;148(20):dev194613
1J:176969 Costello I, Pimeisl IM, Drager S, Bikoff EK, Robertson EJ, Arnold SJ, The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol. 2011 Sep;13(9):1084-91
1*J:232545 Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG, Early patterning and specification of cardiac progenitors in gastrulating mesoderm. Elife. 2014;3
1J:336868 Kokkinopoulos I, Ishida H, Saba R, Ruchaya P, Cabrera C, Struebig M, Barnes M, Terry A, Kaneko M, Shintani Y, Coppen S, Shiratori H, Ameen T, Mein C, Hamada H, Suzuki K, Yashiro K, Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo. PLoS One. 2015;10(10):e0140831
1J:81152 Mukhopadhyay M, Teufel A, Yamashita T, Agulnick AD, Chen L, Downs KM, Schindler A, Grinberg A, Huang SP, Dorward D, Westphal H, Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation. Development. 2003 Feb;130(3):495-505
1*J:53656 Perea-Gomez A, Shawlot W, Sasaki H, Behringer RR, Ang S, HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development. 1999 Oct;126(20):4499-511
1J:157256 Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D, Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. Development. 2010 Jan;137(2):249-59
1J:42014 Saga Y, Hata N, Koseki H, Taketo MM, Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
1*J:55840 Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki Ji, Inoue T, MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development. 1999 Aug;126(15):3437-47
1J:341093 Schule KM, Weckerle J, Probst S, Wehmeyer AE, Zissel L, Schroder CM, Tekman M, Kim GJ, Schlagl IM, Sagar, Arnold SJ, Eomes restricts Brachyury functions at the onset of mouse gastrulation. Dev Cell. 2023 Sep 25;58(18):1627-1642.e7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory